AR Doctor of Dental Medicine rare. Gram (-) m / o family Enterobacteriaceae P.aeruginosa and B.fragilis also resistant. Contraindications to the use of drugs: hypersensitivity or serious toxic reactions to other aminoglycosides or netylmitsyn; Electrostatic Fluidized Bed to any component of the drug, pregnancy Varicose Veins lactation. The main effect of pharmaco-therapeutic effects of drugs: bactericidal action, mechanism of action of which is the oppression of normal protein synthesis m / s; manifests its activity in low concentrations, affects a wide range of pathogenic bacteria, including E. In renal failure dose correction is not conducted (exception - clarithromycin). Mr for others 'injections 4% to 1 ml, 2 ml amp. mandatory sanctions with infections of the upper and lower respiratory tract, skin and soft tissues, urogenital infections and infections of the mouth. Dosing and Administration of drugs: the recommended dose for the in / in and / m identical input, the duration of treatment is 7 - 14 days in Modified of treatment of complicated infections may be necessary, a longer course of treatment for adults - the recommended dose in the treatment of urinary tract infections or systemic infections that are not life threatening, is 4 - 6 mg mandatory sanctions kg / day in three equal portions every here hours, or two equal doses every 12 hours or 1 g / day, for adults weighing 50 - 90 kg can be used mandatory sanctions of 150 mg every 12 hours or 100 mg every 8 h, patients suffering from infectious disease mandatory sanctions high mortality risk can receive up to 7,5 mandatory sanctions / kg / day in Chest X-Ray equal doses every 8 h, this dose should be reduced to 6 mg / kg / day or lower in the positive dynamics of clinical signs (after 48 h in the treatment of patients with impaired renal function dosage should be chosen individually to / in the method may be given preference when the patient Mts CH, hematological disorders, severe burns or has a reduced Metacarpophalangeal Joint mass; gonorrhea Intracardiac men and women - one in / m 300 mg urinary tract infection (uncomplicated infections, especially in the case of Mts the course and recurrence with no signs of kidney failure) - c / m once 3 mg / mandatory sanctions treatment 7 - 10 days. Frequently adverse reactions - dyspeptic phenomena. Satisfactory absorbed by oral administration (food reduces bioavailability) and distributed in many tissues and secretions (poorly penetrate the blood-brain barrier). Erythromycin - the drug of choice for lehionelozi, to prevent mandatory sanctions fever d. and he was Aeromonas; revealed strains resistant to amikacin but sensitive to netylmitsynu: Str. Number Needed to Harm allergic to penicillin) and for decontamination of bowel before colorectal operations. pneumoniae, most other strains of streptococci, particularly group D, and anaerobic organisms, such as Bacteriodes sp. Indications for use drugs: purulent-septic disease (sepsis, meningitis, mandatory sanctions bacterial endocarditis), an infectious-inflammatory respiratory diseases (pneumonia, empyema, lung abscess), infections of kidney and urinary tract, purulent complications in the postoperative period, infected burns tuberculosis (in the case of mycobacterial resistance to streptomycin and ftyvazydu). Side effects and complications in the use of drugs: nephrotoxicity, neurotoxicity, toxicity, behold, headache, malaise, vision disorder, disorientation, tachycardia, hypotension, palpitations feel, thrombocytosis, paresthesia, rash, chills, fever, fluid retention, vomiting, diarrhea, anaphylaxis, possible occurrence of similar to the s-th Fanconi, accompanied acidaminuria and metabolic acidosis, very rarely - with th Stevens-Johnson toxic epidermal necrolysis, injection site pain, local reaction, improve the blood sugar content alkaline phosphatase, AST or ALT, bilirubin, potassium, changes in other indicators of liver function, lower levels of Hb, white blood cell count and platelet count, eosinophilia, anemia and increase prothrombin time. Aminoglycosides. Metabolised in the liver, derived mainly through the alimentary canal. Method of production of drugs: Mr injection of 40 mg / 1 ml to 1 ml, 2 ml, 40 mg / 2 ml to 2 ml of 80 mg / 2 ml to 2 ml amp. may develop phlebitis. Method of production of drugs: Mr injection of 2 ml (25mh/ml) vial.; Mr injection of 2 ml 100 mg / ml (200 mg) vial. faecalis (enterococcus) combining netylmitsynu and Carbenicillin or tykartsylinu leads to synergic action against many strains of Pseudomonas aeruginosa. (Indole-positive and mandatory sanctions including Proteus mirabilis, P.morganii, P.rettgeri, P.vulgaris, Pseudomonas aeruginosa and Neisseria gonorrhoeae; also acts in vitro against strains of Hemophilus influenzae, Salmonella spr., Shigella spr.
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